Molnupiravir
КапсулыAntiviral agent of systemic action
Indications
Treatment of a new coronavirus infection (COVID-19), confirmed by the results of a diagnostic test for SARS-CoV-2, mild to moderate in adult patients with an increased risk of disease progression to severe and not requiring additional oxygen therapy
Contraindications
- hypersensitivity to molnupiravir or any other component of the drug Molnupiravir
- pregnancy or pregnancy planning
- breastfeeding period
- children under 18 years of age
With caution
In patients with severe renal insufficiency (GFR less than 30 ml/min/1.73 m2) and in patients with impaired liver function, monitoring of blood biochemical parameters is necessary.
Usage
The drug Molnupiravir is taken orally regardless of food intake.
Capsules should be swallowed whole, without opening, crushing or chewing them, washed down with a sufficient amount of liquid (for example, a glass of water).
The use of the drug Molnupiravir is possible only under the supervision of a doctor.
Dosage regimen
The following dosage regimen is recommended for the treatment of the new coronavirus infection (COVID-19) caused by the SARS-CoV-2 virus in adults:
- 4 capsules of 200 mg orally 2 times a day (every 12 hours). A single dose is 800 mg. The daily dose is 1600 mg. The duration of the course of treatment is 5 days.
Treatment with Molnupiravir should be initiated as early as possible after the diagnosis of a new coronavirus infection (COVID-19) and/or within 5 days after the first symptoms of the disease appear.
If the next dose of the drug is missed, if the delay in admission is less than 10 hours from the scheduled intake time, then the missed dose should be taken as soon as possible and the usual dosage regimen should be resumed; if the delay in admission is more than 10 hours, then the missed dose should not be taken, and the next dose should be taken at the usual time. The patient should not take a double dose of the drug to compensate for the missed dose.
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Has contraindications. Needs specialist overview.