News 04.10.23

Macitentan, a new drug, has been registered

Mir-Pharm announces successful registration of new orphan drug

Moscow, September 2023


Macitentan belongs to the group of antihypertensive agents, which are used in pulmonary arterial hypertension (PAH - increased pressure in the blood vessels leading from the heart to the lungs) and are used for its long-term treatment.

Mode of action of the drug Macitentan

The drug Macitentan contains the active ingredient - macitentan, which is an antagonist of endothelin receptors, which in turn contributes to vasoconstriction. Macitentan permanently blocks endothelin-1 receptors of smooth muscle cells of pulmonary arteries and prevents pressure increase in the pulmonary artery.



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