Icatibant
РастворA bradykinin B2-receptor blocker drug, an anti-allergic drug used for symptomatic therapy of acute attacks of hereditary angioedema in adults with C1 esterase inhibitor deficiency.
Indications
Icatibant is indicated for the symptomatic treatment of acute attacks of hereditary angioedema (due to C1 esterase inhibitor deficiency) in adults, adolescents and children aged 2 years and older.
Contraindications
Hypersensitivity to the drug components (active substance and excipients), concomitant use of angiotensin-converting enzyme inhibitors, children under 18 years of age (efficacy and safety of use have not been established).
Usage
Icatibant should be administered under the supervision of a qualified health care professional. The decision on the possibility of self-administration of Icatibant by the patient or his/her carer is made by a physician experienced in the diagnosis and treatment of HAE. Patients with clinical manifestations of laryngeal oedema should be urgently hospitalised and should be under medical supervision until the HAE attack is completely resolved. The syringe containing Icatibant is intended for single use only.
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Drugs in the category Allergology
Has contraindications. Needs specialist overview.